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Deamidated Gliadin Peptide (DGP) Antibody, IgA

Ordering Recommendation

Acceptable single screening test for celiac disease. IgA testing recommended to identify IgA deficiency. Use IgA test in individuals who are IgA competent. May be useful in diagnosing children <2 years who test negative for tTG and EMA antibodies. May aid in monitoring adherence to gluten-free diet. Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgA (0097709) is the preferred test for screening patients with suspected celiac disease.

Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon-Sat
Reported
1-2 Days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation:
Collect:
Serum separator tube (SST).
Specimen Preparation:
Separate serum from cells ASAP or within 2 hours of collection. Transport 0.5 mL serum. (Min: 0.3 mL)
Storage/Transport Temperature:
Refrigerated
Unacceptable Conditions:
Plasma or other body fluids. Contaminated, hemolyzed, grossly icteric, or grossly lipemic specimens.
Remarks:
Plasma. Hemolyzed or severely lipemic specimens.
Stability:
After separation from cells:  Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval
19 Units or less
20-30 Units
Negative
Weak Positive
31 Units or greater
Positive
Interpretive Data
Note
Human recombinant tTG antigen is utilized in this assay
CPT Code
86258
Components
Component Chart Name
Deamidated Gliadin Peptide (DGP) Ab, IgA
Component Test Code
0051357
LOINC
63453-5
Aliases
Celiac Disease Antibodies
Coeliac Disease Antib
odies

Deamidated Gliadin Antibodies (DGP)

Deaminated Gliadin Peptide Antibodies

DGP

DGP Ab

DGP IgA

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