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Beta-2 Glycoprotein 1 Antibody, IgA
Ordering Recommendation
Preferred second-line test when seronegative antiphospholipid syndrome (APS) is strongly suspected. Order incrementally or concurrently with other noncriteria antiphospholipid antibody tests. May also be useful in estimating risk of thrombosis and/or pregnancy-related morbidity in patients with SLE.
Mnemonic
B2GPI A
Performed
Mon-Sat
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation:
Collect:
Serum separator tube.
Specimen Preparation:
Separate serum from cells ASAP or within 2 hours of collection.
Storage/Transport Temperature:
Refrigerated.
Unacceptable Conditions:
Plasma or other body fluids. Contaminated, hemolyzed, grossly icteric, or severely lipemic specimens.
Remarks:
Stability:
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
<=20 SAU
Interpretive Data
Compliance Category: FDA
Note
MPL = IgM phospholipid units
CPT Code
86146
Components
Component Chart Name
B2Glycoprotein 1, IgA Antibody
Component Test Code
0050324
LOINC
21108-6
Aliases
Anti-B2-Glycoprotein 1
Anti-B2-Glycoprotein I
Anti-B2-GP 1
Anti-B2-GP I
Anti-B2-GP1
Anti-B2-GPI
Anti-Beta-2-Glycoprotein I
APOH
Apolipoprotein H
B2 IgA
B2-glycoprotein 1 IgA
B2GP1 IgA
Beta 2GP1 Ab
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